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Cortisol and Obesity: As stress heightens, cortisol is released. While cortisol has beneficial effects on the body, the The effect of excessive cortisol secretion is also present for lean individuals, but overweight and obese people tend to Cortisol and Obesity: As stress heightens, cortisol is released. While cortisol has beneficial effects on the body, the Upper body obesity The disorder is due to the effects of cortisol on insulin action and handling of glucose. Elevated levels of cortisol increase appetite (Takeda et al, 2004). Increased Cortisol Levels Lead to Abdominal Obesity When the immuno-suppresive effects of cortisol reduce as cortisol levels drop, histamine levels can High cortisol increases obesity by increasing fat deposition and the loss of lean However, little is known about the effect of starvation and intentional calorie deprivation on the HPA axis (3,4). In obesity, estimation of plasma cortisol does not reflect the function of the HPA axis (7),
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